3-[2-[(1R,4aβ)-2-Methylene-5α-(hydroxymethyl)-5,8aα-dimethyl-6α-hydroxydecalin-1α-yl]ethyl]-2,5-dihydrofuran-2-one
14-Deoxyandrographolide
CAS: 4176-97-0
Molecular Formula: C20H30O4
3-[2-[(1R,4aβ)-2-Methylene-5α-(hydroxymethyl)-5,8aα-dimethyl-6α-hydroxydecalin-1α-yl]ethyl]-2,5-dihydrofuran-2-one - Names and Identifiers
3-[2-[(1R,4aβ)-2-Methylene-5α-(hydroxymethyl)-5,8aα-dimethyl-6α-hydroxydecalin-1α-yl]ethyl]-2,5-dihydrofuran-2-one - Physico-chemical Properties
| Molecular Formula | C20H30O4 |
| Molar Mass | 334.45 |
| Density | 1.15 |
| Melting Point | 176-178℃ |
| Boling Point | 509.5±50.0 °C(Predicted) |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Appearance | Cryst. |
| pKa | 14.89±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD01861504 |
| Physical and Chemical Properties | White powder, soluble in methanol, ethanol, DMSO and other organic solvents, comes from Andrographis paniculata Andrographis paniculata (Burm. f.) Nees. |
3-[2-[(1R,4aβ)-2-Methylene-5α-(hydroxymethyl)-5,8aα-dimethyl-6α-hydroxydecalin-1α-yl]ethyl]-2,5-dihydrofuran-2-one - Reference
| Reference Show more | 1. [IF=3.935] Meng Xia et al."Correlation analysis of physicochemical properties with anti-inflammatory activity of Andrographis paniculata (Burm.f.) Nees based on HPLC-DAD, colorimeter and multivariate statistics: A comprehensive quality evaluation strategy."J Pharmac |
3-[2-[(1R,4aβ)-2-Methylene-5α-(hydroxymethyl)-5,8aα-dimethyl-6α-hydroxydecalin-1α-yl]ethyl]-2,5-dihydrofuran-2-one - Reference Information
| biological activity | 14-deoxyandrographolide is a bioactive component of Andrographis paniculata, which has the function of protecting liver. By inducing the release of TNFRSF1A, 14-deoxyandrographolide gradually desensitizes hepatocytes to TNF-α-mediated apoptosis. |
| Use | for content determination/identification/pharmacological experiments. |
Last Update：2024-04-10 22:29:15
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Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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Product Name: 14-Deoxyandrographolide Visit Supplier Webpage Request for quotationCAS: 4176-97-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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